Presented by Cleveland Public Theatre and The MetroHealth System, ENDependence explores the story of pain management in this country, the kinds of treatment available for those struggling with opioid use disorder, and best methods for responding to the epidemic. Infused with both humor and gravity, and featuring songs and scenes, ENDependence highlights those in our community who are affected by opioid use disorder—from doctors to patients to family members. Interactive in form, ENDependence calls on our community to investigate how we respond on a personal and systemic level to our oldest companion: pain.